TOKSISITAS SENYAWA Β-SITOSTEROL DAN EKSTRAK KULIT BATANG AGLAIA

##plugins.themes.academic_pro.article.main##

Riky Riky

Abstract

Pacar cina (Aglaia odorata Lour) is a plant that is widely used as an traditional medicine because of natural materials they contain. The  study  aims  to  from Pacar cina extracts and toxicity test of each extract and isolated compound by BSLT (Brine Shrimp Lethality Test) method. The method used in the maceration. In this study, the n-hexane, ethyl acetate, methanol extracts and β-sitosterol compound showed toxic effect (LC50 261,17; 110; 266,75 and 100 μg/mL, respectively). The toxicity degree among the three extracts and isolated compound is β-sitosterol > ethyl acetate > n-hexane > methanol.

##plugins.themes.academic_pro.article.details##

How to Cite
Riky, R. (2019). TOKSISITAS SENYAWA Β-SITOSTEROL DAN EKSTRAK KULIT BATANG AGLAIA. Jurnal Insan Cendekia, 5(1, Maret). Retrieved from https://digilib.itskesicme.ac.id/ojs/index.php/jic/article/view/493

References

Setiawati Wiwin, dkk. 2008. Tumbuhan Bahan Pestisida Nabati dan Cara Pembuatannya untuk Pengendalian Organisme Pengganggu Tumbuhan (OPT). Bandung : Balai Penelitian Tanaman Sayuran

Sugijanto, N.E. Beatrice Yodianto, Made N. Kusumajaya, Noor C. Zaini. Aktivitas Antimikroba Dan Analisis Klt-Densitometri Metabolit Fraksi –Fraksi Ekstrak Endofit Dari Aglaia odorata. Berkala Ilmiah Kimia Farmasi, Vol.3 No. 1 Juni 2014

Zhang Heng, et. al 2012. Chemical constituents from Aglaia odorata Lour. Biochemical Systematics and Ecology. Elsivier

Hartanto Satrio, Nurul Hidajati. 2012. Isolasi dan Identifikasi Senyawa Terpen dari Ektrak Kulit Batang Aglaia odorata Lour (Meliaceae). UNESA Journal of Chemistry Vol. 1, No. 1. Surabaya.UNESA.

Kurniawan H. 2012. Uji Toksisitas Akut Ekstrak Metanol Daun Kesum (Polygonum minus H) Terhadap Larva Artemia salina LeachDenganMetode Brine Shrimp Lethality Test (BSLT). Skripsi Program Studi Farmasi Fakultas Kedokteran dan Ilmu Kesehatan Universitas Tanjungpura, Pontianak

Tomayahu Rahma. dkk. 2014. Identifikasi Senyawa Aktif dan Uji Toksisitas Ekstrak Daun Binahong (Anredera cordifolia Ten. Steenis) dengan Metode Brine Shrimp Lethality Test (BSLT). Fakultas MIPA Universitas Negeri Gorontalo.

Novalien Fiergiyanti et al,2015. Analisis Fitokimia dan Toksisitas (Brine Shrimp Lethality Test) Ekstrak Serbuk Sari dari Trigona Incisa. Jurnal Kimia Mulawarman Volume 13 Nomor 1.

Mclaughlin. 1998. The Use of Biological Assays to Evaluate Botanicals. Drug Information Journal. Vol 32: 513-524.

Simes, J. J. H., J. G. Tracey, L. J. webb, and W. J. Dunstan. (1995). An Australian Phytochemical Survey. Commonwealth Scientific and Industrial Research Organization.

Santoni, A. 2009. Elusidasi Struktur Senyawa Metabolit Sekunder Kulit Batang Surian (Toona sinensis) Meliaceae dan Uji Aktivitas Insektisida. Disertasi. Program Pascasarjana Universitas Andalas. Padang.

Dwi. D.D, Mai Efdi and Adlis Santoni (2015), Isolation and elucidation structure major compoundsfrom the leaves of Aglaia odorata Lour, Journal of Chemical and Pharmaceutical Research, 2015, 7(8):121-123

Juniarti, Osmeli D., dan Yuhernita, (2009), Kandungan Senyawa Kimia, Uji Toksisitas (Brine Shrimp Lethality Test) Dari Ekstrak Daun Saga (Abrus precatorius L.) Bagian Kimia, Fakultas Kedokteran, Universitas YARSI, Jakarta 10510, Indonesia

Meyer, B. N, N.R. Ferrigni, J.E. Putman, L.B. Jacobsen, D.E. Nichol dan J.L. Melaughlin. 1982. Brine Shrimp: A Vonvenient General Bioassay for Avtive Plant Constituents. Planta Medica 45:31-34