Typhoid fever is a disease is still a serious in developing countries, especially provincial area east java.In rneast java rate occurrence typhoid fever in clinic and hospitals successive 4.000 cases per month. And rnfrom 1.000 cases per month by death rate 2 %.In typhoid fever patients infected by germs salmonella rntyphi supress any endotoxin on the outer germ of lipopolisakarida will spur…